Ignatius Donnelly was the most widely known Minnesotan of the nineteenth century. As a writer, orator, and social thinker, he enjoyed fame in the U.S. and overseas. As a politician he was the nation's most articulate spokesman for Midwestern populism. Though the highest office he held was that of U.S. congressman, he shaped Minnesota politics for more than thirty years.

Henry Hastings Sibley occupied the stage of Minnesota history for fifty-six active years. He was the territory's first representative in Congress (1849–1853) and the state's first governor (1858–1860). In 1862 he led a volunteer army against the Dakota under Ta Oyate Duta (His Red Nation, also known as Little Crow). After his victory at Wood Lake and his rescue of more than two hundred white prisoners, he was made a brigadier general in the Union Army.