One of the first female professors in the United States, Maria Sanford was an English professor at the University of Minnesota for nearly thirty years. Her exceptional teaching, notable public lectures, and active community leadership led many to call her "the best-loved woman in Minnesota."

Alice Gustava Smith, better known by her students and readers as Sister Maris Stella, taught English at the College of St. Catherine (now St. Catherine University) in St. Paul for nearly fifty years. During that time she also published books of verse that built her reputation as a skilled and spiritual poet.

St. Joseph’s Academy traces its origins to 1851, when the first Sisters of St. Joseph opened a school for girls in a log cabin on the banks of the Mississippi. One hundred and twenty years later, the final St. Joseph’s Academy High School closed its doors. Today, its buildings on Marshall and Western Avenues are on the National Register of Historic Places and still in use.

St. Olaf College is a private liberal arts college in Northfield, Minnesota. It was founded by Norwegian Lutherans in 1874 and continues to thrive as a top-ranking school.

Three Hebrew schools were founded in St. Paul between 1880 and 1920—the era of peak Jewish immigration to the city. Each had its own constituency and neighborhood. After much negotiation, they joined forces in 1956 and took the name Talmud Torah of St. Paul.

In the 1850s and 60s, Thomas Barlow (T. B.) Walker worked his way through school and into Minnesota's lumber industry, where he became unusually successful. He later helped found two of Minneapolis's significant cultural organizations: the public library system and the Walker Art Center.