The Agricultural Extension Service of the United States (AES) began as an educational component of land-grant universities. In Minnesota as in other states, the federally funded and organized services of AES provide practical agricultural training to people outside of a university setting.

Wadena County contains three known fur trade sites. One is located on private property along the Leaf River where Joseph Réaume, an independent fur trader, set up a winter camp in the late eighteenth century. Between 2011 and 2012, the University of Minnesota conducted archaeological surveys and excavations at this location. They confirmed a late-eighteenth century occupation, validating its association with Réaume's 1792 wintering activities.

As Minnesota state legislators met on the evening of March 1, 1881, two days before the end of their twenty-second session, two pages alerted them to a fire in the building. Quick action by lawmakers and nearby residents saved important documents, furnishings, and historical collections. The fire took no lives but destroyed Minnesota's first capitol building.

In 1854, the United States took the mineral-rich lands of northeastern Minnesota Territory from the Ojibwe Nation after the signing of the Treaty of La Pointe. Four years later, it granted to the new state of Minnesota sections 16 and 36 of every one of its townships, either to be held in trust or leased to support state schools. Close to three million acres were dedicated to a public school trust fund, and the iron ore and forest lands of the Ojibwe generated over 85 percent of its value. In 2017, it is worth over a billion dollars.