Begun in 1918 and active until the late 1970s, the Barberry Eradication Program was an unprecedented cooperative effort between the US Department of Agriculture and twelve US states to remove the invasive common barberry bush from major areas of wheat production in the United States. The common barberry bush was a problem because it is a secondary host for the fungus that causes stem-rust disease, the most devastating disease of wheat. Minnesota played the central role in the establishment and operations of the eradication program.

The Basilica of Saint Mary was first known as the Pro-Cathedral of Minneapolis. It cost one million dollars to build and held its first Mass in 1914. In 1926, the Catholic Church made it the first basilica in the United States.

The Battle of Birch Coulee, fought between September 2 and 3, 1862, was the worst defeat the United States suffered and the Dakotas' most successful engagement during the US–Dakota War of 1862. Over thirty hours, approximately 200 Dakota warriors pinned down a Union force of 150 newly recruited US volunteers, militia, and civilians from the area, holding them until Henry Sibley's main army arrived.

On September 23, 1862, United States troops, led by Colonel Henry Sibley, defeated Dakota warriors led by Ta Oyate Duta (His Red Nation, also known as Little Crow) Dakota at the Battle of Wood Lake. The battle marked the end of the U.S.-Dakota War of 1862.

The US Congress ordered the beginning of mail service from Superior to Grand Portage, Minnesota, in 1855, but service was spotty. John Beargrease and his brothers came to the rescue. They began covering a regular mail route between Two Harbors and Grand Marais in 1879.

Pat Bellanger was an Ojibwe activist and a cofounder of the American Indian Movement (AIM) who spent over fifty years fighting for Indigenous rights on a national and local level. Though she often escaped the public eye, her work survives through her children and community, the attendees of survival schools, and the children protected by the Indian Child Welfare Act (1978).

The Beltrami County Poor Farm provided shelter and care for elderly and disabled people from 1902 until 1935, when old-age assistance programs replaced the poor farm system.

Born in 1779 in the Lombardy region of Italy, Giacomo Costantino Beltrami achieved fame and fortune at a young age. When political pressure and personal loss spurred him to leave home, he set out to explore the world. Today he is best known for an account of his travels through present-day Minnesota, and for his claim to have found the source of the Mississippi River.

The National Baseball Hall of Fame credits Charles Albert Bender with inventing the slider, a curveball with extra speed. Like his patented pitch, Bender's life course was a circuitous one, beginning on the White Earth Reservation in northern Minnesota.

Hyman Berman was a University of Minnesota history professor and a popular public historian known widely for his contributions to the Almanac public affairs program on Twin Cities PBS. Although his earliest scholarship focused on labor history, upon arriving in Minnesota in 1961 Berman wrote extensively about Minnesota’s immigrant history, the state’s political parties, and the Jewish experience in Minnesota.

Minneapolis-born Cora Johnstone Best achieved international success as a mountaineer during the 1920s. She was a pioneer in the sport, becoming a licensed guide at a time when women were rarely given the opportunity to be lead climbers.

Founded in 1922, Beth El was the last synagogue to be formed on the North Side of Minneapolis. It was the only one to affiliate with Judaism's Conservative movement. In the 1960s, Beth El, like other North Side synagogues (all of them Orthodox), moved to St. Louis Park.