The northern boundary of the United States is set at the forty-ninth parallel of latitude, extending from the Lake of the Woods to the Rocky Mountains.
The Agriculture School of the University of Minnesota's St. Paul campus, which was known as University Farm, opens with forty-seven students and W. W. Pendergast as principal.
At St. Paul's Episcopal Church in Duluth, an organizational meeting is held to establish a new hospital in the city. Named for today's feast of St. Luke, the hospital is set up in an old blacksmith's shop, and the first patient is admitted on November 18.
Land in central Minnesota is set aside for the Mamaceqtaw (Menominee). The tribe decides not to move from their holdings in Wisconsin and cedes the proposed reservation to the state on May 5, 1854.