Calvin Griffith decides to move his Washington Senators to Minnesota, where the baseball team is renamed the Minnesota Twins.

Edward Calvin Kendall and Philip Showalter Hench, Mayo Clinic doctors, and Tadeus Reichstein, a Swiss doctor, are awarded the Nobel Prize in Medicine for their development of cortisone.

In the seventh game of the World Series, the Minnesota Twins beat the St. Louis Cardinals with a score of 4-2, winning the series 4-3.

Novelist Anne Tyler is born in Minneapolis. She published many popular books, including The Accidental Tourist and Breathing Lessons, for which she was awarded a Pulitzer Prize in 1989.

The Yankton Dakota cede the area around their pipestone quarry in Pipestone County to the United States but retain free access to the quarry grounds.

In an unprecedented move and a milestone in Minnesota's labor history, two hundred and sixty women employed at the clothing factory of Shotwell, Clerihew & Lothman on Second Street in Minneapolis walk out, demanding that piece rates, which had been cut at the first of the year, be restored. Although the company agreed to make small reforms, few of the strikers returned to work. Due to lack of workers or to a boycott by sympathetic community members, Shotwell, Clerihew & Lothman closed its doors a few months later.

Harold E. Stassen is born in West St. Paul. Elected governor at age thirty-two, he became the youngest individual to hold that office, from 1939 to 1943. He resigned as governor to serve as a lieutenant commander in the navy during World War II. His long and distinguished career in public service was overshadowed by a string of defeats as he sought the Republican nomination for president. He died in 2001.

The state senate passes the Minnesota Anti-Lynching Bill, which stipulates that a law enforcement officer can be removed from duty for not stopping a lynching and that damages may be recovered by the victim's family. Promoted by civic activist Nellie G. Francis, the bill is a response to the Duluth lynchings of 1920.

Soldiers at Fort St. Anthony (later called Fort Snelling) view Minnesota's first officially recorded tornado, which damages the barracks' roof.

The Lake Traverse Reservation of Sisseton Wahpeton Dakota—600,000 acres in North and South Dakota, across the western Minnesota border from Browns Valley—is opened to settler-colonists. In a scene reminiscent of the Oklahoma land rush, a gunman shoots a pistol at noon, and the stampede of prospective settlers begins.